Koji Takeda Selected Research

Mitral Valve Annuloplasty

10/2015	B-type natriuretic peptide response and reverse left ventricular remodeling after surgical correction of functional mitral regurgitation in patients with advanced cardiomyopathy.
4/2012	Serial multidetector computed tomography assessment of left ventricular reverse remodeling, mass, and regional wall stress after restrictive mitral annuloplasty in dilated cardiomyopathy.
4/2012	Left ventricular mechanics following restrictive mitral annuloplasty for functional mitral regurgitation: two-dimensional speckle tracking echocardiographic study.
3/2012	The extent of early left ventricular reverse remodelling is related to midterm outcomes after restrictive mitral annuloplasty in patients with non-ischaemic dilated cardiomyopathy and functional mitral regurgitation.
9/2011	Restrictive mitral annuloplasty with or without surgical ventricular restoration in ischemic dilated cardiomyopathy with severe mitral regurgitation.
9/2011	Does stringent restrictive annuloplasty for functional mitral regurgitation cause functional mitral stenosis and pulmonary hypertension?
1/2011	Left ventricular basal myocardial scarring detected by delayed enhancement magnetic resonance imaging predicts outcomes after surgical therapies for patients with ischemic mitral regurgitation and left ventricular dysfunction.
9/2010	Mechanism of beneficial effects of restrictive mitral annuloplasty in patients with dilated cardiomyopathy and functional mitral regurgitation.
8/2010	Assessment of regional myocardial wall stress before and after surgical correction of functional ischaemic mitral regurgitation using multidetector computed tomography and novel software system.
4/2008	Left ventricular reconstructive surgery in ischemic dilated cardiomyopathy complicated with cardiogenic shock.

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Koji Takeda Research Topics

Disease

52	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2021 - 12/2002
48	Heart Failure 10/2022 - 02/2008
36	Cardiogenic Shock 01/2022 - 04/2008
20	Hemorrhage 01/2022 - 02/2012
20	Neoplasms (Cancer) 01/2019 - 04/2004
13	Infections 12/2022 - 01/2016
12	Stroke (Strokes) 06/2022 - 01/2016
12	Mitral Valve Insufficiency (Mitral Regurgitation) 12/2020 - 08/2010
12	Neutropenia 05/2019 - 01/2003
11	Disease Progression 01/2022 - 12/2008
11	Thrombosis (Thrombus) 01/2022 - 01/2017
11	Lung Neoplasms (Lung Cancer) 05/2019 - 04/2004
10	Febrile Neutropenia 05/2019 - 12/2002
10	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2017 - 01/2003
7	Myocardial Infarction 01/2022 - 02/2010
7	Primary Graft Dysfunction 01/2020 - 06/2017
7	Diarrhea 05/2019 - 12/2002
7	Thrombocytopenia (Thrombopenia) 01/2018 - 01/2003
6	Shock 01/2022 - 04/2016
6	COVID-19 01/2021 - 01/2020
6	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 11/2018 - 09/2010
6	Cardiomyopathies (Cardiomyopathy) 12/2017 - 04/2008
6	Adenocarcinoma 09/2013 - 04/2004
5	Pulmonary Hypertension 11/2022 - 09/2011
5	Renal Insufficiency (Renal Failure) 06/2022 - 11/2013
5	Tricuspid Valve Insufficiency (Insufficiency, Tricuspid Valve) 04/2022 - 02/2016
5	Ischemia 01/2022 - 11/2014
4	Obesity 01/2022 - 01/2018
4	Endotoxemia 01/2021 - 01/2019
4	Inflammation (Inflammations) 01/2021 - 01/2019
4	Colorectal Neoplasms (Colorectal Cancer) 12/2018 - 09/2011
4	Fibrosis (Cirrhosis) 11/2018 - 02/2010
4	Vomiting 05/2018 - 12/2010
4	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2017 - 06/2006
4	Neoplasm Metastasis (Metastasis) 07/2015 - 01/2013
3	Myocarditis (Carditis) 03/2022 - 01/2016
3	Death (Near-Death Experience) 03/2022 - 01/2018
3	Coronary Artery Disease (Coronary Atherosclerosis) 01/2022 - 01/2020
3	Heart Arrest (Cardiac Arrest) 01/2022 - 01/2018
3	Congenital Heart Defects (Congenital Heart Defect) 01/2021 - 10/2016
3	Chronic Renal Insufficiency 12/2020 - 01/2012
3	Clinical Deterioration 12/2020 - 01/2018
3	Hemolysis 01/2020 - 01/2017
3	Diabetes Mellitus 11/2019 - 08/2015
3	Dyspnea (Shortness of Breath) 08/2019 - 02/2008
3	Fatigue 08/2019 - 06/2010
3	Nausea 05/2018 - 12/2010
3	Cardiac Arrhythmias (Arrythmia) 01/2018 - 08/2006
3	Pneumonia (Pneumonitis) 08/2016 - 09/2008
3	Leukopenia 12/2010 - 01/2003
3	Anemia 07/2010 - 01/2003
2	Pulmonary Embolism 01/2022 - 03/2013

Drug/Important Bio-Agent (IBA)

14	Carboplatin (JM8)FDA LinkGeneric 01/2019 - 12/2002
13	Cisplatin (Platino)FDA LinkGeneric 05/2018 - 05/2010
11	Biomarkers (Surrogate Marker)IBA 01/2021 - 12/2008
11	ErbB Receptors (EGF Receptor)IBA 01/2021 - 12/2008
11	Docetaxel (Taxotere)FDA Link 09/2019 - 08/2006
9	Irinotecan (Camptosar)FDA LinkGeneric 12/2018 - 12/2002
9	Gefitinib (Iressa)FDA Link 11/2017 - 04/2004
8	PlatinumIBA 05/2019 - 04/2004
7	Pharmaceutical PreparationsIBA 01/2020 - 06/2006
7	Paclitaxel (Taxol)FDA LinkGeneric 01/2019 - 12/2010
6	CreatinineIBA 10/2022 - 07/2013
6	NivolumabIBA 01/2021 - 01/2016
6	Tyrosine Kinase InhibitorsIBA 09/2018 - 04/2009
5	Hemoglobins (Hemoglobin)IBA 01/2022 - 01/2003
5	Prostaglandins DIBA 01/2020 - 06/2017
5	Pemetrexed (MTA)FDA Link 11/2017 - 11/2010
5	Topotecan (Hycamtin)FDA LinkGeneric 08/2016 - 01/2003
5	amrubicinIBA 04/2014 - 08/2007
4	Amiodarone (Amiodarona)FDA LinkGeneric 01/2020 - 11/2017
4	Erlotinib Hydrochloride (CP 358,774)FDA Link 11/2017 - 12/2008
3	Interleukin-6 (Interleukin 6)IBA 01/2020 - 02/2010
3	S-1 plus cisplatinIBA 09/2018 - 05/2010
3	Etoposide (VP 16)FDA LinkGeneric 08/2016 - 01/2014
3	Anti-Bacterial Agents (Antibiotics)IBA 03/2016 - 10/2008
3	Gemcitabine FDA Link 02/2012 - 10/2010
3	Vinorelbine (Navelbine)FDA LinkGeneric 02/2012 - 08/2006

Therapy/Procedure

69	Heart-Assist Devices 12/2022 - 06/2012
55	Therapeutics 01/2022 - 07/2007
32	Extracorporeal Membrane Oxygenation 03/2022 - 05/2015
32	Drug Therapy (Chemotherapy) 04/2021 - 04/2004
27	Heart Transplantation (Grafting, Heart) 03/2022 - 02/2015
10	Transplantation 01/2022 - 04/2008
10	Mitral Valve Annuloplasty 10/2015 - 04/2008
7	Radiotherapy 01/2018 - 11/2007
6	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2019 - 12/2008
5	Patient Readmission 01/2022 - 10/2014
5	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2021 - 02/2008
5	Combination Drug Therapy (Combination Chemotherapy) 08/2016 - 12/2002
4	Renal Replacement Therapy (Therapies, Renal Replacement) 10/2021 - 12/2016
4	Palliative Care (Palliative Therapy) 01/2021 - 04/2019
3	Cardiopulmonary Resuscitation (CPR) 01/2022 - 01/2018
3	Cannula 01/2022 - 05/2015
3	Contraindications 10/2021 - 11/2015
3	Chemoradiotherapy 01/2021 - 11/2007
3	Sternotomy 01/2021 - 10/2016
2	Endarterectomy (Thromboendarterectomy) 11/2022 - 04/2022
2	Renal Dialysis (Hemodialysis) 06/2022 - 09/2012
2	Tracheostomy 06/2022 - 11/2017